Relationship between blood pressure and humoral factors in inhibition of hypertension with long-term administration of antihypertensive agents in SHRs from prehypertensive stage [proceedings].

plasma renin activities (PPA) were measured before treatment and 5 weeks and 10 weeks after the beginning of the administration of the above-mentioned diet. The data were compared with those of non-treated age-matched SHR controls. Each group consisted of more than 8 SHRs and blood samples were taken immediately after decapitation. PCA was measured by double isotope derivative method and PRA by bioassay method. Occasional blood pressure (BP) measurements were done by the tail-pulse-pickup method.